On the one hand, most of the problems of gas chromatography are due to lack of maintenance of the instrument, such as failure to replace consumables (injection pad, liner, O-ring, gas purification device, etc.) in time; on the other hand, it is due to failure to follow normal procedures and Instrument operation is required, such as the length of the chromatographic column installation is not equal; again, it may be caused by the analysis process of the operator, such as improper sample preparation, unskilled manual injection, etc.; finally, it may be caused by laboratory environment and instrument failure, including The laboratory circuit is not well grounded, the pipeline is leaking, and the parts are damaged.
 
    In the daily application of gas chromatography, everyone generally focuses on key components such as chromatographic columns and detectors, while the equally important inlet maintenance and related parameter settings are often ignored by everyone. This article starts from the related concepts of gas chromatography. , To introduce its principles, in order to provide ideas for the solution of gas-related problems, deficiencies and deficiencies, I hope colleagues to criticize and correct.
 
    As an expensive analytical instrument, gas chromatography is hoped to be used for a longer period of time, so daily maintenance and good usage habits are essential. This also allows the gas chromatography instrument to work normally and maintain good detection results. Today, the editor will summarize 10 tips to get the daily maintenance of gas chromatography for your reference.
 
    1. Operate in accordance with the procedures in the instrument manual
 
    This is mainly for newly purchased and installed instruments. It is not only necessary to check whether the spare parts and spare parts are complete, but also to check whether the manual is complete, and these materials must be properly kept for future reference. Before operating the instrument independently, be sure to read the relevant instructions carefully and operate in strict accordance with the regulations. This is the precursor to good instrument analysis, and it is also convenient to communicate with the manufacturer when there is a problem with the instrument. Especially for instruments that are still under warranty, the manufacturer will not repair them for free if they malfunction or are damaged due to improper operation. Sometimes the cost is quite objective.
 
    2. Ensure the air tightness of the gasification chamber gasket
 
    1. The life of the silicone rubber gasket of the gas chromatograph inlet is related to the temperature of the vaporization chamber. Generally, it can be used dozens of times. When the silicone rubber gasket leaks, it will cause the fluctuation of the baseline, and the reproducibility of the analysis will be poor, which will make the results Not allowed.
 
    2. Due to the excessive puncture of the sampler, the silicon rubber pad debris enters the vaporization chamber. If there are too many debris, it will affect the stability of the baseline at high temperature or form ghost peaks. Therefore, in order to ensure the normal analysis of the analysis, please frequently replace the sealing gasket and frequently check the air tightness of the vaporization chamber.
 
    3. Frequent leak detection of the gas circuit
 
    1. Under normal circumstances, leak detection has been performed when purchasing a new instrument. However, if sensitivity is reduced, retention time is prolonged, or a wavy baseline is found during use, the leak detection should be performed again, especially if the hydrogen gas circuit is changed. Leak detection should be frequent to avoid danger.
 
    2. Some control valves use "O"-shaped rubber rings, which may leak due to long-term wear; the injection port silica gel pad is not frequently replaced, the chromatographic column is not connected properly... it may leak, so you must always check for leaks!
 
    4. Gas chromatography often cleans the vaporization chamber or liner
 
    1. Due to long-term use, a large amount of high boiling point substances are often accumulated in the vaporization chamber and liner of the gas chromatograph. If a high boiling point substance is analyzed for a certain time, excess peaks will escape, which will affect the analysis. Therefore, organic solvents should be used frequently. Clean the vaporization chamber and liner.